Hello everyone! I am thinking about participating in a clinical trial that focuses on glutamate in the brain. It is conducted by Biohaven Pharma and has been promoted by nOCD. Is anyone on this site participating in a clinical trial?

Do you see therapy for ocd?

No.

I have signed up for the MKET trial at Stanford (if you scroll down a couple days you’ll find the thread about it). I haven’t heard back about being accepted yet. Im currently on a medication called Namenda that works on glutamate - it’s been an absolute game-changer for me. No trial necessary - my shrink prescribed it as I have had several years of bad luck with SSRIs in the past. I encourage you to give it a try!

Thank you for the info on Namenda. I will check with my doctor. I hope you get accepted into the clinical trial at Stanford. Glutamate seems to be a big player in everything that I am reading.

I am participating in it

You should consider signing up in the form and then connect with a site to learn more

@mjs which trial are you participating in?

P- how big of a game-changer with Namenda? Any side effects?

@Nole - I could not tolerate the side effects of any SSRIs. I tried several. So I can’t compare to those. But the namenda was huge. The obsessions became more distant and I was able to get more perspective and was less anxious. My ocd is extremely severe and ingrained - I just started treatment - so I still struggle sometimes. But it’s been a huge difference from before with namenda. The biggest side effect I noticed was more energy - which was a good thing for me. Just generally less depressed and more motivated. It sounds like part of the treatment but it was unexpected - even by my doc. It changed my life.

I am glad it is working for you. SSRI’s always made me tired and didn’t do a whole lot. I am excited about what the researchers are finding about glutamate in the synapses. May be a matter of time before a breakthrough is discovered!

@Nole - I think it’s about time researchers come out of the rabbit hole of SSRIs and branch out! They aren’t the panacea doctors tend to think they are. They don’t work for a large percentage of the population.

Amen to that!